Here's a review of Combray that is not your average skin care product review, in the sense of the amount of scrutiny the reviewer applied:

http://www.organiclifestylemagazine.com/issue-9/combray.html

I think it was about a 2 month process in all putting Combray to the test: sunburn, wound healing, insect bites, and more. The results with mosquito bites is kind of a new data point for us, but another person has also mentioned it. Combray really passed with flying colors.

The natural, organic, etc. versus synthetic question is raised regarding Oxofulleram, as the review is in a digital magazine called Organic Lifestyle Magazine, but they don't come across as close-minded, just the opposite. One of the ways I thought of to explain Oxofulleram was to consider the technology theoretically necessary to produce it - one could dig up the raw carbon from e.g., a coal seam, then "cook" it with an oil in a fairly primitive fashion and that would basically be it, plus or minus some very lucky choices of what you added to the cooking pot. Chemistry is cooking, and cooking is chemistry, pretty much.

The structure exists in nature, and just has to meet the right other ingredients. Not that that is any better or worse than a purely synthetic structure.